The Chemical Sensitivity Foundation - Research Bibliography

Antelman, S.M. “Time-Dependent Sensitization in Animals: A Possible Model of Multiple Chemical Sensitivity in Humans.” Toxicology and Industrial Health 10, nos. 4-5 (July-October 1994):335-342.

Association of Occupational and Environmental Clinics. “Advancing the Understanding of Multiple Chemical Sensitivity.” Toxicology and Industrial Health 8, no. 4 (1992):1.

Ashford, N., Heinzow, B., Lüütjen, K., Marouli, C., Møølhave, L., Möönch, B., Papadopoulos, S., Rest, K., Rosdahl, D., Siskos, P., Velonakis, E., et al. “Chemical Sensitivity in Selected European Countries: An Exploratory Study.” A Report to the European Commission.  Ergonomia, 1995.

ATSDR (Agency for Toxic Substances and Disease Registry). “Proceedings of the Conference on Low-Level Exposure to Chemicals and Neurobiologic Sensitivity.” Toxicology and Industrial Health 10, nos. 4-5 (1994):25.

Bartha, L., Baumzweiger, W., Buscher, D., Callender, M., Dahl, K., Davidoff, A., et al. “Multiple Chemical Sensitivity: A 1999 Consensus.” Archives of Environmental Health 54, no. 3 (1999): 147-149.

Bascom, R. “Multiple Chemical Sensitivity: A Respiratory Disorder.” Toxicology and Industrial Health 8, no. 4 (1991):221-228.

Bascom, R., Meggs, W., Frampton, M., Hudnell, K., Killburn, K., Kobal, G., Medinsky, M., Rea, W. “Neurogenic Inflammation: With Additional Discussion of Central and Perceptual Integration of Nonneurogenic Inflammation.” Environmental Health Perspectives 105, Suppl. 2 (1997):531-537.

Bell, I.R. “Clinically Relevant EEG Studies and Psychophysiological Findings: Possible Neural Mechanisms for Multiple Chemical Sensitivity.” Toxicology 111 (1996):101-117.

Bell, I.R. “White Paper: Neuropsychiatric Aspects of Sensitivity to Low-Level Chemicals: A Neural Sensitization Model.” Toxicology and Industrial Health 10, nos. 4-5 (July-October 1994):277-312.

Bell, I.R., Baldwin, C.M., Schwartz, G.E. “Sensitization Studies in Chemically Intolerant Individuals: Implications for Individual Difference Research.” Annals of the New York Academy of Science 453 (2001):38-47.

Bell, I., Baldwin, C., Fernandez, M., Schwartz, G. “Neural Sensitization Model for Multiple Chemical Sensitivity: Overview of Theory and Empirical Evidence.” Toxicology and Industrial Health 15, nos. 3-4 (1999):295-304.

Bell, I., Rossi, J., Gilbert, M., Kobal, G., Morrow, L., Newlin, D., Sorg, B., Wood, R. “Testing the Neural Sensitization and Kindling Hypothesis for Illness from Low Levels of Environmental Chemicals.” Environmental Health Perspectives 105, Suppl. 2 (1997):539-547.

Buchwald, D., Garrity, D. “Comparison of Patients with Chronic Fatigue Syndrome, Fibromyalgia, and Multiple Chemical Sensitivities.” Archives of Internal Medicine 154 (1994): 2049-2053.

Callender, T.J., Morrow, L., Submaranium, K. “Evaluation of Chronic Neurological Sequelae After Acute Pesticide Poisoning Using Brain SPECT Scans.” Journal of Toxicology and Environmental Health 41 (1994):275-284.

Caress, S., Steinemann, A. “A Review of a Two-Phase Population Study of Multiple Chemical Sensitivities.” Environmental Health Perspectives 111, no. 12 (2003):1490-1497.

Caress, S., Steinemann, A., Waddick, C. “Symptomatology and Etiology of Multiple Chemical Sensitivities in the Southeastern United States.” Archives of Environmental Health: An International Journal 57, no. 5 (2002):429-436.

Cone, J., Sult, T. “Acquired Intolerance to Solvents Following Pesticide/Solvent Exposure in a Building: A New Group of Workers at Risk for Multiple Chemical Sensitivity.” Toxicology and Industrial Health 8, no. 4 (1992):29-39.

Costa, L., Li, W., Richter, R., Shih, D., Lusis, A., Furlong, C. “The Role of Paraoxonase (PON1) in the Detoxication of Organophosphates and Its Human Polymorphism.” Chemico-Biological Interactions 119-120 (1999):429-438.

Cowan, J., Sinton, C.M., Varley, A.W., Wians, F.H., Haley, R.W., Munford, R.S. “Gene Therapy to Prevent Organophosphate Intoxication.” Toxicology and Applied Pharmacology 173, no. 1 (May 15, 2001): 1-6.

Cullen, M., Pace, P., Redlich, C.  “The Experience of the Yale Occupational and Environmental Medicine Clinics with Multiple Chemical Sensitivities,” 1986-1991.  Toxicology and Industrial Health 8 (1992):15-19.

Davidoff, A., Fogarty, L. “Psychogenic Origins of Multiple Chemical Sensitivity Syndrome: A Critical Review of the Research Literature.” Archives of Environmental Health 49, no. 5 (1994):316-325.

Davidoff, A., Keyl, P. “Symptoms and Health Status in Individuals with Multiple Chemical Sensitivities Syndrome from Four Reported Sensitizing Exposures and a General Population Comparison Group.” Archives of Environmental Health 51, no. 3 (1996):201-213.

Davidoff, A.L., Meggs, W. “Development of Multiple Chemical Sensitivities in Laborers After Acute Gasoline Fume Exposure in an Underground Tunneling Operation.” Archives of Environmental Health 53, no.3 (1998):183-189.

Doty, R., Deems, D., Frye, R., Pelberg, R., Shapiro, A. “Olfactory Sensitivity, Nasal Resistance, and Autonomic Function in Patients with Multiple Chemical Sensitivities.”  Archives of Otolaryngology—Head and Neck Surgery 114 (1988):1422-1427.

Fernandez, M., Bell, I., Schwartz, G. “EEG Sensitization During Chemical Exposure in Women With and Without Chemical Sensitivity of Unknown Etiology.” Toxicology and Industrial Health 15, nos. 3-4 (1999):305-312.

Fiedler, N., Kipen, H., Natelson, B., Ottenweller, J. “Chemical Sensitivities and the Gulf War: Department of Veterans Affairs Research Center in Basic and Clinical Science Studies of Environmental Hazards.” Regulatory Toxicology and Pharmacology 24 (1996):S129-S138.

Fincher, E.F., Chang, T.S., Harrell, E.H., Kettkecut, M.C., Rea, W.J., Johnson, A.R., Hickey, H.C.,  Simon, T.R. “Comparison of Single Photon Computed Tomography Findings in Cases of Healthy Adults and Solvent-Exposed Adults.” American Journal of Industrial Medicine 31 (1997):4-14.

Galland, L. “Biochemical Abnormalities in Patients with Multiple Chemical Sensitivities.” Occupational Medicine 2, no. 4 (October-December 1987):713-720.

Gordon, B.R. “Approaches to Testing for Food and Chemical Sensitivities.” Otolaryngology Clinics of North America 36, no. 5 (October 2003):917-940. Haley, R., Billecke, S., La Du, B. “Association of Low PON1 Type Q (Type A) Arylesterase Activity with Neurologic Symptom Complexes in Gulf War Veterans.” Toxicology and Applied Pharmacology 157, no. 3 (1999):227-233.

Heuser, G. “Diagnostic Markers in Clinical Immunotoxicology and Neurotoxicology.” Editorial. Journal of Occupational Medicine and Toxicology 1, no. 4 (1992):v-x.

Heuser, G., Mena, I., Alamous, F. “Neurospect Findings in Patients Exposed to Neurotoxic Chemicals.” Toxicology and Industrial Health 10, nos. 4-5 (1994):461-571.

Heuser, G., Mena, I. “Neurospect in Neurotoxic Chemical Exposure. Demonstration of Long-Term Functional Abnormalities.” Toxicology and Industrial Health 14, no. 6 (1998):813-827.

Heuser, G., Wu, J.C. “Deep Subcortical (Including Limbic) Hypermetabolism in Patients with Chemical Intolerance: Human PET Studies.” Annals of the New York Academy of Sciences 933 (March 2001):319-322.

Ionescu, G., Merk, M., Bradford, R. “Simple Chemiluminesence Assays for Free Radicals in Venous Blood and Serum Samples: Results in Atopic, Psoriasis, MCS, and Cancer Patients.” Forsch Komplementarmed 6, no. 6 (December 1999):294-300.

Kailen, E.W., Brooks, C.R. “Systemic Toxic Reactions to Soft Plastic Food Containers.” Medical Annals of D.C. 32 (1963):1-8.

Kilburn K. “Effects of Diesel Exhaust on Neurobehavioral and Pulmonary Functions.” Archives of Environmental Health 55, no.1 (January/February 2000).

Kimata, H. “Effect of Exposure to Volatile Organic Compounds on Plasma Levels of Neuropeptides, Nerve Growth Factor and Histamine in Patients with Self-Reported Multiple Chemical Sensitivity.” International Journal of Hygiene and Environmental Health 207, no. 2 (February 2004):159-63.

Kimata, H. “Exposure to Road Traffic Enhances Allergic Skin Wheal Responses and Increases Plasma Neuropeptides and Neurotrophins in Patients with Atopic Eczema/Dermatitis Syndrome.”  International Journal of Hygiene and Environmental Health 207, no 1. (January 2004) 45-49.

Kipen, H.M., Hallman, W., Kang, H., Fiedler, N., Natelson, B.H. “Prevalence of Chronic Fatigue and Chemical Sensitivities in Gulf Registry Veterans.” Archives of Environmental Health 54, no. 5 (September-October 1999):309-311.

Kruetzer, R., Neutra, R., Lashuay, N. “Prevalence of People Reporting Sensitivities to Chemicals in a Population-Based Survey.” American Journal of Epidemiology 150, no. 1 (1999):1-12.

Lax, M., Henneberger, P. ‘Patients with Multiple Chemical Sensitivities in an Occupational Health Clinic: Presentation and Follow-up.” Archives of Environmental Health 50, no. 6 (1995):425-431.

Levallois, P. Neutra, R., Lee, G., Hristoa, L.  “Study of Self-reported Hypersensitivity to Electromagnetic Fields in California.”  Environmental Health Perspectives 110, Suppl. 4 (August 2002): 619-23.

Lieberman, A.D., Craven, M.R. “Reactive Intestinal Dysfunction Syndrome (RIDS) Caused by Chemical Exposures.” Archives of Environmental Health 54, no. 5 (September-October 1999):365-366.

McFadden, S. “Phenotype Variation in Xenobiotic Metabolism and Adverse Environmental Response: Focus on Sulfur-Dependant Detoxification Pathways.” Toxicology 111 (1996):43-65.

McKeown-Eyssen, G., Baines, C., Cole, D.E., Riley, N., Tyndale, R.F., Marshall, L, Jazmaji, V. “Case-Control Study of Genotypes in Multiple Chemical Sensitivity: CYP2D6, NAT1, NAT2, PON1, PON2 and MTHFR.” International Journal of Epidemiology (July 15, 2004).

 Meggs, W.J. “Hypothesis for Induction and Propagation of Chemical Sensitivity Based on Biopsy Studies.” Review. Environmental Health Perspectives 105 (March 1997).

Meggs, W.J. “Neurogenic Switching: A Hypothesis for a Mechanism for Shifting the Site of Inflammation in Allergy and Chemical Sensitivity.” Environmental Health Perspectives 103, no. 1 (January 1995):54-56.

Meggs, W. “RADS and RUDS—The Toxic Induction of Asthma and Rhinitis.” Clinical Toxicology 32, no. 5 (1994):487-501.

Meggs, W., Cleveland, C. “Rhinolaryngoscopic Examination of Patients with the Multiple Chemical Sensi-tivity Syndrome.” Archives of Environmental Health 41, no. 1 (1993):14-18.

Meggs, W., Dunn, K., Bloch, R., Goodman, P., Davidoff, L. “Prevalence and Nature of Allergy and Chemical Sensitivity in a General Population.” Archives of Environmental Health 51, no. 4 (1996): 275-282.

Meggs, W.J., Elsheik, T., Metzger, W.J., Albernaz, M., Bloch, R.M. “Nasal Pathology and Ultrastructure in Patients with Chronic Airway Inflammation Following an Irritant Exposure.” Journal of Toxicology-Clinical Toxicology 34, no. 4 (1996):383-396.

Miller, C.S. “Possible Models for Multiple Chemical Sensitivity: Conceptual Issues and Role of the Limbic System. Advancing the Understanding of Multiple Chemical Sensitivity.” Association of Occupational and Environmental Clinics. Toxicology and Industrial Health 8, no. 4 (1992):181-202.

Miller, C.S. “White Paper: Chemical Sensitivity: History and Phenomenology.” Toxicology and Industrial Health 10, no. 4-5 (1994):253-276.

Miller, C.S., Gammage R.B., Jankovic, J.T. “Exacerbation of Chemical Sensitivity: A Case Study.” Toxicology and Industrial Health 15, nos. 3-4 (April-June 1999):398-402.

Miller, C.S., Mitzel, H. “Chemical Sensitivity Attributed to Pesticide Exposure Versus Remodeling.” Archives of Environmental Health 50, no. 2 (1995):119.

Miller, C.S. “Toxicant-Induced Loss of Tolerance: An Emerging Theory of Disease?” Environmental Health Perspectives 105, Suppl. 2 (1997):445-453.

Miller, C., Prihoda, T. “The Environmental Exposure and Sensitivity Inventory (EESI): A Standardized Approach for Measuring Chemical Intolerances for Research and Applications.” Toxicology and Industrial Health 15 (1999):370-385.

Miller, C., Prihoda, T. “A Controlled Comparison of Symptoms and Chemical Intolerances Reported by Gulf War Veterans, Implant Recipients, and Persons with Multiple Chemical Sensitivity.” Toxicology and Industrial Health 15 (1999):386-397.

Miller, C., Ashford, N., Doty, R., Lamielle, M., Otto, D., Rahill, A., Wallace, L. “Empirical Approaches for the Investigation of Toxicant-Induced Loss of Tolerance.” Environmental Health Perspectives 105, Suppl. 2 (1997):515-519.

Miller, C., Gammage, R., Jankovic, J. “Exacerbation of Chemical Sensitivity: A Case Study.” Toxicology and Industrial Health 15 (1999):398-402.

Millqvist, E., Bengtsson, U., Lowhagen, O. “Provocations with Perfume in the Eyes Induce Airway Symptoms in Patients with Sensory Hyperreactivity.” Allergy 54, no. 5 (May 1999):495-499.

Nethercott, J., Davidoff, L., Curbow, B., Abbey, H. “Multiple Chemical Sensitivities Syndrome: Toward a Working Case Definition.” Archives of Environmental Health 48 (1993):19-26.

Overstreet, D.H., Djuric, V. “A Genetic Rat Model of Cholinergic Hypersensitivity: Implications for Chemical Intolerance, Chronic Fatigue, and Asthma.” Annals of the New York Academy of Science 933 (March 2001):92-102.

Overstreet, D., Miller, C., Janowsky, D., Russell, R. “Potential Animal Model of Multiple Chemical Sensitivity with Cholinergic Supersensitivity.” Toxicology 111 (1996):119-134.

Pall, M.L.  “Elevated Nitric Oxide-Peroxynitrite Theory of Multiple Chemical Sensitivity: Central Role of N-Methyl-D-Aspartate Receptors in the Sensitivity Mechanism.” Environmental Health Perspectives 111, no. 12 (September 2003):1461-1464.

Randolph, T.G. “Clinical Manifestations of Individual Susceptibility to Insecticides and Related Materials.”  Industrial Medicine and Surgery 34 (February 1965):134-142.

Randolph, T.G. “Dynamics, Diagnosis, and Treatment of Food Allergy.” Review. Otolaryngology Clinics of North America 7, no. 3 (October 1974):617-635.

Randolph, T.G. “Ecologic Orientation in Medicine: Comprehensive Environmental Control in Diagnosis and Therapy.” Annals of Allergy 23 (January 1965):7-22.

Randolph, T.G. “Human Ecology and Susceptibility to the Chemical Environment.” Annals of Allergy 19 (May 1961):518-540.

Randolph, T.G. ‘Human Ecology and Susceptibility to the Chemical Environment: Air Pollution.” Annals of Allergy 19 (June 1961):657-677.

Randolph, T.G. “Human Ecology and Susceptibility to the Chemical Environment.” Annals of Allergy 19 (July 1961):779-799.

Randolph, T.G. “Human Ecology and Susceptibility to the Chemical Environment.” Annals of Allergy 19 (August 1961):908-929.

Rea, W.J., Didriksen, N., Simon, T.R., Pan, Y., Fenyves, E.J., Griffiths, B. “Effects of Toxic Exposure to Molds and Mycotoxins in Building-Related Illnesses.” Archives of Environmental Health 58, no. 7 (July 2003):399-405.

Rea, W.J. “Environmentally Triggered Cardiac Disease.” Annals of Allergy 40 (April 1978):243-251.

Rea, W.J. “Environmentally Triggered Small Vessel Vasculitis.” Annals of Allergy 38 (April 1977):245-251.

Rea, W.J. “Environmentally Triggered Thrombophlebitis.” Annals of Allergy 37, no. 2 (August 1976):101-109.

Rea, W.J., Peters, D.W., Smiley, R.E., Edgar, R., Greenberg, M., Fenyves, E. “Recurrent Environmentally Triggered Thrombophlebitis: A Five-Year Follow-up.” Annals of Allergy 47, no. 5, pt.1 (November 1981):338-44.

Rogers, W.R., Miller, C.S., Bunegin, L.  “A Rat Model of Neurobehavioral Sensitization to Toluene.” Toxicology and Industrial Health 15, nos. 3-4 (April-June 1999):356-369.

Ross, G.H. “Clinical Characteristics of Chemical Sensitivity: An Illustrative Case History of Asthma and MCS.” Environmental Health Perspectives 105, Suppl. 2 (March 1997):437-441.

Ross, G.H. “History and Clinical Presentation of the Chemically Sensitive Patient.” Toxicology and Industrial Health 8, no. 4 (July-August 1992):21-28.

Ross, G.H., Rea, W.J., Johnson, A.R., Hickey, D.C., Simon, T.R. “Neurotoxicity in Single Photon Computed Tomography Brain Scans of Patients Reporting Chemical Sensitivities.” Toxicology and Industrial Health 15 (1999):415-420.

Rossi, J. “Sensitization Induced by Kindling and Kindling-Related Phenomena as a Model for Multiple Chemical Sensitivity.” Toxicology 111, nos. 1-3 (July 17, 1996):87-100.

Shirakawa, S., Ishikawa, S., Miyata, M., Rea, W.J., Johnson, A.R. “A Pupillographical Study on the Presence of Organochlorine Pesticides in Autonomic Nerve Disturbance.” Nippon Ganka Gakkai Zasshi 94, no. 4 (April 1990):418-423.

Simon, T.R., Hicket, D.C., Fincher, C.E., Johnson, A.R., Ross, G.H., Rea, W.J. “Single Photon Computed Tomography of the Brain in Patients with Chemical Sensitivities.” Toxicology and Industrial Health 10, nos. 4-5 (1994):573-577.

Simon, T.R., Rea, W.J.  “Use of Functional Brain Imaging in the Evaluation of Exposure to Mycotoxins and Toxins Encountered in Desert Storm/Desert Shield.” Archives of Environmental Health 58, no. 7 (July 2003):406-409.

Sorg, B.A., Hochstatter, T. “Behavioral Sensitization After Repeated Formaldehyde Exposure in Rats.” Toxicology and Industrial Health 15, nos. 3-4 (April-June 1999):346-355.

Sorg, B.A. “Multiple Chemical Sensitivity: Potential Role for Neuralsensitization.” Review. Critical Reviews in Neurobiology 13, no. 3 (1999):283-316.

Sorg, B. “Proposed Animal Model for Multiple Chemical Sensitivity in Studies with Formalin.” Toxicology 111 (1996):135-145.

Stephens, R., Spurgeon, A., Calvert, I., et al. “Neuropsychological Effect of Long-Term Exposure to Organophosphates in Sheep Dip.” Lancet 3459 (1995):1135-1139.

Ternesten-Hasseus, E., Bende, M., Millqvist, E. “Increased Capsaicin Cough Sensitivity in Patients with Multiple Chemical Sensitivity.” Journal of Occupational and Environmental Medicine 44, no. 11 (November 2002).

Thrasher, J.D., Heuser, G., Broughton, A. “Immunological Abnormalities in Humans Chronically Exposed to Chlorpyrifos.” Archives of Environmental Health 57, no. 3 (May-June 2002):181-187.

Thrasher, J.D., Vojdani, A., Cheung, G., Heuser, G. “Evidence for Formaldehyde Antibodies and Altered Cellular Immunity in Subjects Exposed to Formaldehyde in Mobile Homes.” Archives of Environmental Health 42, no. 6 (November-December 1987):347-350.

Welch, L.S., Sokas, R. “Development of Multiple Chemical Sensitivity After an Outbreak of Sick-Building Syndrome.” Toxicology and Industrial Health 8, no. 4 (1991):47-65.

Wiesmuller, G.A., et al. “Nasal Function in Self-Reported Chemically Intolerant Individuals.” Archives of Environmental Health 57, no. 3 (May-June 2002):247-254.

Ziem, G.E. “Multiple Chemical Sensitivity: Treatment and Follow-up with Avoidance and Control of Chemical Exposures. Advancing the Understanding of Multiple Chemical Sensitivity.” Association of Occupational and Environmental Clinics. Toxicology and Industrial Health 8, no. 4 (1992):181-202.

Ziem, G.E., McTamney, J. “Profile of Patients with Chemical Injury and Sensitivity.” Environmental Health Perspectives 105, Suppl. 2 (March 1997):417-436.